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A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Development of Halo Nevus Around Nevus Spilus as a Central Nevus, and the Concurrent Vitiligo
Yoon Young Kim1, Mi Yeon Kim1, Tae Yoon Kim1
1Department of Dermatology, Kangnam St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Abstract:
Halo nevus is a benign melanocytic nevus that is surrounded by a hypopigmented zone. The most frequent association with halo nevus is vitiligo, and this also appears in nearby regions, as well as at other remote sites. Although the mechanism for developing the depigmentation around nevus spilus is uncertain an immunologic process may be responsible for the finding of inflammatory infiltrates of the upper dermis in the depigmented lesions. We report here on a 13-year-old boy who showed a depigmented zone around a nevus spilus on the right side of his neck with simultaneous vitiligo lesions on the face.
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