Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Computed Tomography01:10

Computed Tomography

9.4K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
9.4K
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

585
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
585
Phase Contrast and Differential Interference Contrast Microscopy01:26

Phase Contrast and Differential Interference Contrast Microscopy

15.0K
Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
15.0K
Glaucoma: Overview01:25

Glaucoma: Overview

1.6K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.6K
X-ray Imaging01:24

X-ray Imaging

11.0K
German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...
11.0K
Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

12.1K
Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
12.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association between Intravenous Ketamine Treatment and Cognitive Function in Patients with Treatment-Resistant Depression: A Double-Blind, Randomized, Placebo-Controlled Trial.

Pharmacopsychiatry·2026
Same author

A case of cardiac lymphangioma: diagnosis suggested by cardiac CT and MRI and successful conservative management.

Journal of cardiology cases·2026
Same author

Association of Multimodal Intracoronary Imaging-Derived Plaque Morphology with the Pathophysiological Disease Patterns Assessed by the Quantitative Flow Ratio-Pullback Pressure Gradient.

Journal of atherosclerosis and thrombosis·2026
Same author

Age and sex-dependent alteration in AMPA receptor density in living human brain.

European journal of nuclear medicine and molecular imaging·2026
Same author

Determinants of myocardial extracellular volume fraction derived from coronary CT angiography in patients with chronic coronary syndrome.

Journal of cardiovascular computed tomography·2026
Same author

Comprehensive Endotyping of Patients With Angina and Nonobstructive Coronary Arteries: A Report From the J-CMD.

Journal of the American Heart Association·2026

Related Experiment Video

Updated: Mar 19, 2026

Thinned-skull Cortical Window Technique for In Vivo Optical Coherence Tomography Imaging
07:28

Thinned-skull Cortical Window Technique for In Vivo Optical Coherence Tomography Imaging

Published on: November 19, 2012

15.8K

Guidewire shadow artifacts in optical coherence tomography.

Takayuki Niida1, Tadashi Murai1, Tetsumin Lee1

  • 1Department of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, Tsuchiura, Japan.

Minerva Cardioangiologica
|June 16, 2016
PubMed
Summary
This summary is machine-generated.

New guidewires designed for optical coherence tomography (OCT) imaging reduce artifacts. This specialized guidewire minimizes shadow artifacts, improving coronary imaging interpretation.

More Related Videos

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
11:21

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography

Published on: January 15, 2013

12.0K
Author Spotlight: Advancements in In Vivo and Ex Vivo Retinal Imaging for Improved Glaucoma Diagnosis and Treatment
07:02

Author Spotlight: Advancements in In Vivo and Ex Vivo Retinal Imaging for Improved Glaucoma Diagnosis and Treatment

Published on: June 30, 2023

2.3K

Related Experiment Videos

Last Updated: Mar 19, 2026

Thinned-skull Cortical Window Technique for In Vivo Optical Coherence Tomography Imaging
07:28

Thinned-skull Cortical Window Technique for In Vivo Optical Coherence Tomography Imaging

Published on: November 19, 2012

15.8K
Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
11:21

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography

Published on: January 15, 2013

12.0K
Author Spotlight: Advancements in In Vivo and Ex Vivo Retinal Imaging for Improved Glaucoma Diagnosis and Treatment
07:02

Author Spotlight: Advancements in In Vivo and Ex Vivo Retinal Imaging for Improved Glaucoma Diagnosis and Treatment

Published on: June 30, 2023

2.3K

Area of Science:

  • Cardiovascular Imaging
  • Medical Device Engineering

Background:

  • High-resolution optical coherence tomography (OCT) reveals previously unseen guidewire artifacts in coronary imaging.
  • These artifacts complicate image interpretation and necessitate artifact reduction strategies.

Purpose of the Study:

  • To evaluate how guidewire size and structure influence artifact formation during OCT imaging.
  • To introduce and assess a novel guidewire engineered to minimize artifacts for optimal OCT imaging.

Main Methods:

  • Guidewire artifacts were assessed using silicon tubes simulating coronary arteries and OCT imaging.
  • Artifact angles from four guidewire types, including a novel design, were evaluated.
  • Clinical data from 20 patients undergoing OCT with different guidewires were analyzed.

Main Results:

  • Artifact angles decreased with smaller guidewire diameters.
  • Specific polymer structures created complex artifacts impacting image interpretation.
  • The novel guidewire demonstrated fewer artifacts and was suitable for clinical use.

Conclusions:

  • Guidewire size and structure significantly affect artifact generation in OCT imaging.
  • A specialized guidewire was developed, producing fewer shadow artifacts than conventional options.
  • The novel guidewire facilitates improved OCT imaging quality in clinical settings.