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Updated: Mar 19, 2026

A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
Published on: August 16, 2018
Exploring the gold mine: [Au]-catalysed transformations of enynals, enynones and enynols
A Leela Siva Kumari1, Alla Siva Reddy1, K C Kumara Swamy1
1School of Chemistry, University of Hyderabad, Hyderabad 500 046, Telangana, India. kckssc@uohyd.ac.in kckssc@yahoo.com.
Abstract:
Gold catalysed synthesis of carbo-/hetero-cyclic compounds is currently a topic of intense activity thanks to the unique properties bestowed upon gold by relativistic effects, the potential of which has been realised mainly during the past two decades. This review will dwell upon the reactions involving gold catalysis in which enynal, enynone or enynol is one of the reacting partners. Most often these reactions lead to fused hetero-/homo-cycles under mild conditions with environmentally benign byproducts. Thus an opportunity for the organic community to develop new methodologies, efficient asymmetric variants, and application in total synthesis by [Au]-catalysis has emerged.
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