Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Therapy01:28

Drug Therapy

382
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
382
Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

653
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
653
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

344
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
344
Psychosis and Antipsychotic Drugs: Overview01:28

Psychosis and Antipsychotic Drugs: Overview

1.1K
The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic...
1.1K
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists01:30

Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists

807
Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
807
Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

57
Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
57

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Vitamin D: What's the Proper Dose?

Journal of the American Geriatrics Society·2026
Same author

Improving Telehealth Transition of Care Programs Focused on Readmission Reduction.

Journal of patient safety·2025
Same author

SHARING Choices: Lessons Learned from a Primary-Care Focused Advance Care Planning Intervention.

Journal of pain and symptom management·2023
Same author

Using Machine Learning to Capture Quality Metrics from Natural Language: A Case Study of Diabetic Eye Exams.

Methods of information in medicine·2021
Same author

Differential Prescribing of Antimuscarinic Agents in Older Adults with Cognitive Impairment.

Drugs & aging·2018
Same author

A Community-Based Collaborative Care Model to Improve Functional Health in Underserved Community-Dwelling Older Adults.

Journal of aging and health·2017

Related Experiment Video

Updated: Mar 19, 2026

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit
06:52

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit

Published on: September 30, 2020

10.8K

Cognitive Dysfunction, Medication Management, and the Risk of Readmission in Hospital Inpatients.

Ryan E Anderson1,2, Stanley J Birge1

  • 1Division of Geriatrics and Nutritional Science, Department of Medicine, Washington University School of Medicine, Saint Louis, Missouri.

Journal of the American Geriatrics Society
|June 16, 2016
PubMed
Summary
This summary is machine-generated.

Cognitive dysfunction increases early hospital readmission risk in older adults managing their own medications. This risk is amplified for those on more than seven medications, highlighting a need for targeted interventions.

Keywords:
cognitionhospital readmissionmedications

More Related Videos

Development of a Virtual Reality Assessment of Everyday Living Skills
10:32

Development of a Virtual Reality Assessment of Everyday Living Skills

Published on: April 23, 2014

19.4K
Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
05:16

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Published on: June 10, 2025

750

Related Experiment Videos

Last Updated: Mar 19, 2026

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit
06:52

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit

Published on: September 30, 2020

10.8K
Development of a Virtual Reality Assessment of Everyday Living Skills
10:32

Development of a Virtual Reality Assessment of Everyday Living Skills

Published on: April 23, 2014

19.4K
Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
05:16

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Published on: June 10, 2025

750

Area of Science:

  • Gerontology
  • Neuroscience
  • Health Services Research

Background:

  • Older adults independently managing medications are at risk for adverse health outcomes.
  • Cognitive dysfunction, especially executive dysfunction, can impair medication management.
  • Early hospital readmission is a significant concern in geriatric care.

Purpose of the Study:

  • To investigate if cognitive dysfunction, specifically executive function deficits, predicts early hospital readmission in older adults managing their own medications.
  • To assess the impact of medication management complexity on this relationship.

Main Methods:

  • A prospective observational study was conducted with 452 adults aged 65+ discharged home.
  • Cognitive function was assessed using the Short Blessed Test (SBT) and Trail-Making Test Part B (TMT-B).
  • Logistic regression analyzed the association between cognitive performance, medication management, and 30-day readmission.

Main Results:

  • Decreased SBT and TMT-B scores were associated with increased 30-day readmission odds in self-medicating older adults.
  • For those on >7 medications, cognitive impairment significantly elevated readmission risk (SBT: +16%, TMT-B: +15% per unit decrease).

Conclusions:

  • Cognitive dysfunction, particularly executive dysfunction, is an independent risk factor for early readmission in older adults managing medications.
  • The number of medications interacts with cognitive function to further increase readmission risk.
  • Identifying cognitive deficits can improve risk stratification for preventing early hospital readmissions.