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Cognitive Translation Using the Rodent Touchscreen Testing Approach.

M Hvoslef-Eide¹, S R O Nilsson², L M Saksida²

¹Department of Psychology, University of Cambridge, Cambridge, CB2 3EB, UK. mh473@cam.ac.uk.

Current Topics in Behavioral Neurosciences

|June 17, 2016

Summary

This summary is machine-generated.

Bridging the translational gap in cognitive research requires consistent assessment methods. The rodent touchscreen platform offers a standardized approach for evaluating cognitive deficits in both animals and humans, improving therapeutic development for neurological and psychiatric conditions.

Keywords:

Cognition Human Mouse Rat Touchscreen Translation

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Last Updated: Mar 19, 2026

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Published on: January 30, 2026

Area of Science:

Neuroscience
Cognitive Psychology
Translational Medicine

Background:

Developing treatments for cognitive deficits in psychiatric and neurodegenerative diseases is crucial but challenging.
Discrepancies in cognitive function assessment between animal models and human studies hinder translational progress.
The rodent touchscreen testing platform is emerging as a solution to bridge this gap.

Purpose of the Study:

To introduce the rodent touchscreen testing platform as a translational tool for cognitive research.
To highlight successful cross-species translations of cognitive tasks using this platform.
To emphasize the potential of touchscreen technology in advancing cognitive neuroscience.

Main Methods:

Utilizing a rodent touchscreen testing platform for cognitive assessments.
Adapting and validating established cognitive tasks for touchscreen interfaces.
Comparing performance on tasks like paired associate learning (PAL), 5-choice serial reaction time task (5-CSRTT), rodent continuous performance task (rCPT), and reversal learning across species.
Assessing the neurocognitive validity of touchscreen tasks.

Main Results:

Demonstrated successful cross-species translation of key cognitive tasks using the touchscreen platform.
Provided specific examples of tasks (PAL, 5-CSRTT, rCPT, reversal learning) effectively translated.
Established the utility of the touchscreen approach in standardizing cognitive assessments.

Conclusions:

The rodent touchscreen platform effectively bridges the translational gap in cognitive research.
This technology facilitates more accurate assessment of cognitive deficits relevant to human diseases.
The touchscreen approach is poised for wider adoption in translational cognitive research due to its validity and consistency.