Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Renal Corpuscle01:20

Renal Corpuscle

8.4K
The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
8.4K
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

718
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
718
Renal Tubule and Collecting Duct01:24

Renal Tubule and Collecting Duct

4.3K
The renal tubule is divided into three parts: the proximal convoluted tubule (PCT), the Loop of Henle (LOH), and the distal convoluted tubule (DCT).
Proximal Convoluted Tubule (PCT):
The PCT is the initial segment of the renal tubule, extending from the Bowman's capsule that encloses the glomerulus. Its convoluted structure and microvilli-lined cells increase the surface area for reabsorption. The PCT reabsorbs glucose, amino acids, sodium, and water from the filtrate, ensuring essential...
4.3K
External Anatomy of the Kidney01:21

External Anatomy of the Kidney

4.5K
The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
4.5K
Renal Drug Excretion: Tubular Reabsorption01:25

Renal Drug Excretion: Tubular Reabsorption

1.0K
Tubular reabsorption, a process occurring post-glomerular filtration of drugs in the renal tubule, is a critical determinant of drug half-life. During the process of renal excretion, as the glomerular filtrate progresses to the distal convoluted tubule (DCT), drugs that are highly permeable, lipophilic, and nonionized undergo passive reabsorption from the tubular fluid into the surrounding peritubular capillaries. This reabsorption process restricts their elimination through the kidneys. This...
1.0K
Renal Drug Excretion: Tubular Secretion01:28

Renal Drug Excretion: Tubular Secretion

1.1K
Active tubular secretion is a robust, energy-demanding process that utilizes carrier systems to transport drugs into renal tubules. The active renal secretion systems include the organic anion transporter (OAT) for weak acids and the organic cation transporter (OCT) for weak bases. Structurally similar drugs can compete for the same transporter, potentially leading to drug accumulation and toxicity. However, this principle can be exploited therapeutically. One example is probenecid (Probalan),...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A unique dataset of immunological and bacteriological test results from experimental infection of European badgers <i>(Meles meles)</i> with <i>Mycobacterium bovis</i>.

Data in brief·2026
Same author

A uniform tissue-clearing framework and mesoSPIM-ultra enable cm-scale single-neuron tracing.

bioRxiv : the preprint server for biology·2026
Same author

Zenflow spring system for benign prostatic hyperplasia - 24 month outcomes of the ZEST pilot studies.

Prostate cancer and prostatic diseases·2026
Same author

CT Hounsfield Unit Measurements Around the Hip and Their Utility for Opportunistic Screening: A Systematic Review.

Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews·2026
Same author

Probing individual quantum emitters in bulk semiconductors via photonic nanojets.

Science advances·2026
Same author

Effect of Poly-γ-glutamic Acid on Kinetics of Enamel Demineralization in vitro at pH 4.0, 4.5 and 5.0.

Calcified tissue international·2026

Related Experiment Video

Updated: Mar 19, 2026

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
09:31

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses

Published on: March 30, 2015

9.3K

Giant renal oncocytoma.

Julien Al Shakarchi, Iain Wharton, Amgad Youssef

    Radiology Case Reports
    |June 17, 2016
    PubMed
    Summary

    A large kidney tumor was initially suspected to be renal cell carcinoma. However, histological examination revealed it to be a rare giant oncocytoma, challenging initial diagnostic assumptions.

    Area of Science:

    • Nephrology
    • Oncology
    • Pathology

    Background:

    • Renal cell carcinoma (RCC) is the most common kidney malignancy.
    • Oncocytomas are benign kidney tumors, typically smaller than 3 cm.
    • Distinguishing between RCC and oncocytoma preoperatively can be challenging.

    Observation:

    • A 70-year-old male presented with a large right kidney lesion detected via ultrasonography.
    • Computed tomography (CT) confirmed a substantial renal tumor.
    • Clinical and radiological data suggested a high probability of renal cell carcinoma.

    Findings:

    • Histological examination unexpectedly revealed the large renal tumor to be an oncocytoma.
    • This specific case represents a giant oncocytoma, significantly larger than typical presentations.
    Keywords:
    CT, computed tomographyMRI, magnetic resonance imaging

    More Related Videos

    Author Spotlight: Developing a Bedside Protocol for Kidney and Genitourinary Ultrasonography
    03:19

    Author Spotlight: Developing a Bedside Protocol for Kidney and Genitourinary Ultrasonography

    Published on: June 21, 2024

    2.6K
    Modeling Spontaneous Metastatic Renal Cell Carcinoma mRCC in Mice Following Nephrectomy
    11:27

    Modeling Spontaneous Metastatic Renal Cell Carcinoma mRCC in Mice Following Nephrectomy

    Published on: April 29, 2014

    17.3K

    Related Experiment Videos

    Last Updated: Mar 19, 2026

    In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
    09:31

    In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses

    Published on: March 30, 2015

    9.3K
    Author Spotlight: Developing a Bedside Protocol for Kidney and Genitourinary Ultrasonography
    03:19

    Author Spotlight: Developing a Bedside Protocol for Kidney and Genitourinary Ultrasonography

    Published on: June 21, 2024

    2.6K
    Modeling Spontaneous Metastatic Renal Cell Carcinoma mRCC in Mice Following Nephrectomy
    11:27

    Modeling Spontaneous Metastatic Renal Cell Carcinoma mRCC in Mice Following Nephrectomy

    Published on: April 29, 2014

    17.3K
  • The tumor's size and imaging characteristics mimicked malignant renal neoplasms.

    • Implications:

    • Giant oncocytomas can present as large renal masses, mimicking renal cell carcinoma.
    • This case highlights the importance of histological confirmation for definitive diagnosis.
    • Accurate preoperative differentiation remains a challenge, impacting surgical and treatment strategies.