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Hashimoto's encephalopathy

Joana Ramalho, Mauricio Castillo

    Radiology Case Reports
    |June 17, 2016
    PubMed

    Insights

    Hashimoto's encephalopathy can present with unusual MRI findings in the brain. While steroid treatment improves symptoms and imaging, some neurological deficits may remain.

    Area of Science:

    • Neurology
    • Neuroimaging
    • Endocrinology

    Background:

    • Hashimoto's encephalopathy is an autoimmune condition associated with thyroid disease.
    • It can present with diverse neurological symptoms and variable neuroimaging findings.

    Observation:

    • A case of Hashimoto's encephalopathy with atypical magnetic resonance imaging (MRI) findings is presented.
    • T2-weighted MRI revealed bilateral, symmetric hyperintensities in the mesial temporal lobes and basal ganglia.

    Findings:

    • Steroid therapy led to clinical improvement and partial resolution of MRI abnormalities.
    • Persistent memory deficits and residual MRI abnormalities were noted despite treatment.

    Implications:

    • This case highlights the potential for atypical and partially reversible MRI changes in Hashimoto's encephalopathy.
    • It underscores the importance of considering autoimmune thyroid disease in patients with unexplained neurological and neuroimaging findings.
    • Long-term monitoring may be necessary due to potential persistent deficits.
    Keywords:
    HE, Hashimoto's encephalopathyMRI, magnetic resonance imaging

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