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Updated: Mar 19, 2026
Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
Published on: June 18, 2021
Pseudosubarachnoid hemorrhage in a 42-year-old male with meningitis
Abstract:
Pseudosubarachnoid hemorrhage is the appearance of subarachnoid hemorrhage on CT imaging with no source of blood found on further evaluation, including lumbar puncture and autopsy. The mechanism leading to this finding is poorly understood, and clinicians should consider this finding in the right clinical setting, such as cryptococcal meningitis. We present a case of an immunocompromised patient found to have a pseudosubarachnoid hemorrhage.
Insights
Pseudosubarachnoid hemorrhage mimics subarachnoid bleeding on CT scans without a clear source. This case highlights its occurrence in an immunocompromised patient, suggesting consideration in specific clinical contexts like cryptococcal meningitis.
Area of Science:
- Neurology
- Radiology
- Infectious Diseases
Background:
- Subarachnoid hemorrhage (SAH) is a critical condition often diagnosed via CT scans.
- Pseudosubarachnoid hemorrhage (PSAH) presents as SAH on CT but lacks an identifiable bleeding source.
- The underlying mechanisms of PSAH remain poorly understood.
Observation:
- This report details a case of PSAH in an immunocompromised patient.
- The patient's clinical presentation necessitated careful diagnostic evaluation.
- Cryptococcal meningitis was a relevant clinical consideration in this scenario.
Findings:
- CT imaging revealed findings consistent with subarachnoid hemorrhage.
- Extensive further investigations, including lumbar puncture, failed to identify a source of bleeding.
- The final diagnosis considered PSAH in the context of the patient's immunocompromised state and clinical presentation.
Implications:
- PSAH requires careful consideration in the differential diagnosis of SAH, especially in specific patient populations.
- Understanding the mechanisms of PSAH is crucial for accurate diagnosis and management.
- This case underscores the importance of integrating imaging findings with clinical context in diagnosing rare neurological conditions.
