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RNA helicase DP103 and TAK1: a new connection in cancer
Eun Myoung Shin1, Motomi Osato2, Alan Prem Kumar3
1Cancer Science Institute of Singapore; National University of Singapore; Singapore ; Institute of Molecular and Cellular Biology; ASTAR, Singapore.
No abstract available in PubMed .
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Cells are regularly exposed to mutagens—factors in the environment that can damage DNA and generate mutations. UV radiation is one of the most common mutagens and is estimated to introduce a significant number of changes in DNA. These include bends or kinks in the structure, which can block DNA replication or transcription. If these errors are not fixed, the damage can cause mutations, which in turn can result in cancer or disease depending on which sequences are...
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