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Association of synthetic model peptides with phospholipid vesicles induced by a membrane potential
A I de Kroon1, J de Gier, B de Kruijff
1Centre for Biomembranes and Lipid Enzymology, University of Utrecht, The Netherlands.
Biochimica Et Biophysica Acta
|June 6, 1989
Abstract:
Hydrophobic model peptides, consisting of 5 or 6 amino acids and carrying a net positive charge at the amino terminus, exhibit a dramatically increased association with large unilamellar egg-PC vesicles upon application of a valinomycin-induced K+ diffusion potential, negative inside. The association of the peptides is largely reversible, apparent from a release of peptide upon dissipation of the membrane potential.