Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pharmacocavernometry: a modified papaverine test.

I K Dickinson1, J P Pryor

  • 1St Peter's Hospital, London.

British Journal of Urology
|May 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The comparative ultrastructure of the epididymis in monkeys and man: A search for a suitable animal model for studying epididymal physiology in primates.

American journal of primatology·2020
Same author

Evaluation of the pressure leak test in increasing the lifespan of flexible ureteroscopes.

International journal of clinical practice·2013
Same author

Laparoscopic management of iatrogenic bladder injury and bladder stone formation following laparoscopic inguinal herniorrhaphy.

Hernia : the journal of hernias and abdominal wall surgery·2008
Same author

Fertility considerations in the patient with testis cancer.

Current opinion in urology·2006
Same author

Use of the 'labelled key-ring clock': a simple technique for urethral-bladder neck anastomosis.

BJU international·2003
Same author

Validity of PSA, free/total PSA ratio and complexed/total PSA ratio measurements in men with acute urinary retention.

Prostate cancer and prostatic diseases·2002

The modified papaverine test, combined with pharmacocavernometry, helps identify impotence causes. This method distinguishes between psychogenic, neurogenic, arterial, and venous-related erectile dysfunction for better diagnosis.

Area of Science:

  • Urology
  • Andrology
  • Vascular Medicine

Background:

  • The papaverine test is a standard diagnostic tool for erectile dysfunction (impotence).
  • A negative response to papaverine alone can indicate either arterial insufficiency or venous leakage, necessitating further investigation.
  • Differentiating the cause of impotence is crucial for effective treatment selection.

Purpose of the Study:

  • To evaluate the efficacy of pharmacocavernometry, integrating the papaverine test with an artificial erection test, in diagnosing the etiology of impotence.
  • To refine the diagnostic capabilities for distinguishing between psychogenic, neurogenic, arteriogenic, and venogenic erectile dysfunction.
  • To assess the utility of a modified papaverine test in providing more detailed etiological information.

Main Methods:

Related Experiment Videos

  • Pharmacocavernometry was performed on 126 patients presenting with impotence.
  • Intracorporeal pressure was monitored after an 80 mg papaverine injection.
  • Saline infusion was administered 10 minutes post-injection to detect venous leakage, classifying responses into five types.

Main Results:

  • Five distinct response patterns were identified, correlating with specific causes of impotence.
  • Type 1 and 2 responses indicated psychogenic or neurogenic impotence.
  • Type 3 responses suggested an arteriogenic cause, while Type 4 and 5 responses identified significant venous leakage.

Conclusions:

  • The modified papaverine test, incorporating pharmacocavernometry, offers enhanced diagnostic accuracy for erectile dysfunction.
  • This integrated approach effectively differentiates between various underlying causes of impotence, including vascular and non-vascular origins.
  • The study supports the use of this modified test for more precise etiological determination in impotence investigations.