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Institutional Policy Changes to Prevent Cardiac Toxicity Associated With Bupivacaine Penile Blockade in Infants
Richard N Yu1, Constance S Houck, Alfonso Casta
1From the *Department of Urology, Boston Children's Hospital, Boston, Massachusetts; and †Department of Anesthesiology, Preoperative and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts.
Insights
Dorsal penile nerve blocks with bupivacaine are common for infant penile surgery. A retrospective analysis revealed a high complication rate at our institution, leading to policy changes that have since eliminated these complications.
Area of Science:
- Pediatric Anesthesiology
- Pain Management
- Surgical Analgesia
Background:
- Dorsal penile nerve block is a standard analgesic technique for infant penile surgery.
- Bupivacaine is frequently used due to its efficacy and long duration.
- Concerns exist regarding rapid systemic absorption of bupivacaine and potential adverse effects.
Observation:
- A retrospective analysis of medical records was conducted.
- The incidence of complications from dorsal penile blockade was evaluated at a specific institution.
- The observed complication rate was 0.075%.
Findings:
- The complication rate at this institution was significantly higher than previously reported.
- This elevated incidence prompted a review and revision of institutional policy.
- The updated policy has successfully eliminated complications associated with penile blocks.
Implications:
- Institutional policy changes can effectively mitigate risks associated with local anesthetic administration.
- Careful monitoring and procedural adjustments are crucial for patient safety in pediatric surgery.
- Further research may explore alternative anesthetic agents or techniques to further enhance safety profiles.
Abstract:
Dorsal penile nerve block is a widely used method of analgesia for infants undergoing penile surgery. Because of its potency, extended duration of action, and lack of vasoconstriction, bupivacaine remains the most commonly used local anesthetic. Rapid systemic absorption of bupivacaine, however, has been associated with profound central nervous system and cardiovascular side effects, including cardiac arrest. As determined by retrospective medical record analysis, the incidence of complications associated with dorsal penile blockade in our institution was 0.075%. This was significantly higher than previously reported prompting a change in institutional policy that has eliminated penile block complications.
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