Rice Bran Oil Decreases Total and LDL Cholesterol in Humans: A Systematic Review and Meta-Analysis of Randomized...

Area of Science:

• Nutrition Science
• Cardiovascular Health
• Dietary Oils

Background:

• Cardiovascular disease (CVD) is a growing global health concern.
• Elevated blood lipids are key risk factors for CVD.
• Vegetable oils, like rice bran oil, are investigated for their potential cardioprotective effects.

Purpose of the Study:

• To systematically review and meta-analyze the effects of rice bran oil consumption on human lipid profiles.
• To quantify the impact of rice bran oil on various blood lipid parameters relevant to CVD risk.

Main Methods:

• A systematic literature search was conducted across multiple databases (PubMed, Scopus, etc.) until November 2015.
• Included 11 randomized controlled trials meeting eligibility criteria.
• Extracted data on lipid profile components including LDL-C, HDL-C, TC, TAG, and others.

Main Results:

• Rice bran oil consumption significantly reduced LDL-C (low-density lipoprotein cholesterol) by -6.91 mg/dl and TC (total cholesterol) by -12.65 mg/dl.
• A notable increase in HDL-C (high-density lipoprotein cholesterol) was observed in men (6.65 mg/dl).
• No significant effects were found on other measured lipid profile components like TAG, apoA, apoB, Lp(a), or cholesterol ratios.

Conclusions:

• Consumption of rice bran oil effectively lowers LDL-C and TC concentrations, contributing to CVD prevention and management.
• Rice bran oil demonstrates beneficial effects on HDL-C levels, particularly in men.
• Further research may be needed to explore effects on other lipid markers.