[Immunologic aspects of macrolide antibiotics]

The authors investigated in an experimental and clinical study the part played by the macrolide antibiotic, tylosine, in the elevated immunological reactivity of the present population to Erythromycin. The first assembled results justify the statement that tylosine used in veterinary practice (sometimes without control) may indice acrossed immunological reactivity against Erythromycin. The authors discuss also other undesirable manifestations after Erythromycin administration. The assembled data confirm the need of an aimed and controllable administration of antimicrobial preparations in human as well as in veterinary medicine.