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Updated: Mar 19, 2026

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Published on: June 2, 2015
Diagnostic Performance of Routine Brain MRI Sequences for Dural Venous Sinus Thrombosis
D Patel1, M Machnowska1, S Symons1
1From the Department of Medical Imaging, University of Toronto, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Routine MRI can detect dural venous sinus thrombosis (DVST) with high specificity. This study found routine MRI sequences effective for diagnosing DVST, even without clinical suspicion, aiding early detection in high-risk patients.
Area of Science:
- Neuroradiology
- Medical Imaging
- Neurology
Background:
- Dural venous sinus thrombosis (DVST) can be suggested by routine MRI.
- This study evaluates routine MRI's diagnostic performance for DVST.
Purpose of the Study:
- Assess routine MRI performance for DVST diagnosis.
- Evaluate interrater reliability of routine MRI findings.
- Focus on superior sagittal, transverse, and sigmoid sinuses.
Main Methods:
- Retrospective case series of 429 patients.
- Routine MRIs reviewed independently by 3 neuroradiologists.
- Contrast-enhanced MRV and CTV used as gold standard.
- Interrater reliability assessed using kappa coefficient.
Main Results:
- DVST present in 16.8% of cases (72/429).
- Routine MRI sequences showed 79.2% sensitivity and 89.9% specificity.
- Moderate interrater reliability (κ = 0.50) observed.
Conclusions:
- Routine MRI can suggest DVST with high specificity.
- Effective even in patients without clinical suspicion.
- Useful for identifying DVST in high-risk individuals.
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