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Primary thyroid leiomyosarcoma: A case report and literature review
Zhen-Yu Zou1, Ning Ning2, Song-Yan Li1
1Department of General Surgery, Chinese People's Liberation Army General Hospital, Beijing 100853, P.R. China.
Oncology Letters
|June 18, 2016
Summary
Primary thyroid leiomyosarcoma (LMS) is a rare cancer. This case report details an elderly male patient
Area of Science:
- Oncology
- Pathology
Background:
- Primary thyroid leiomyosarcoma (LMS) is an exceptionally rare soft tissue malignancy.
- Fewer than 22 cases have been documented in medical literature.
- Accurate diagnosis is challenging due to frequent misdiagnosis as anaplastic carcinoma.
Purpose of the Study:
- To report a rare case of primary thyroid LMS in an 83-year-old male.
- To review the existing literature on thyroid LMS.
- To emphasize the importance of integrated clinical, imaging, and pathological assessment for diagnosis.
Main Methods:
- Case presentation of an 83-year-old male with a rapidly growing neck mass.
- Review of relevant medical literature on primary thyroid LMS.
- Analysis of clinical, imaging, and pathological data for diagnostic confirmation.
Main Results:
- The patient presented with a rapidly enlarging neck mass.
- The patient underwent two thyroid lobectomies and two cycles of immunotherapy.
- The patient succumbed to the disease 5 months post-second surgery, highlighting the aggressive nature.
Conclusions:
- Accurate diagnosis of primary thyroid LMS requires a multidisciplinary approach.
- This case underscores the rarity and diagnostic challenges of thyroid LMS.
- Further research is needed to improve diagnostic accuracy and treatment strategies.
