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A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Phytoactive Eremophilanes Produced by the Weed Pathogen Drechslera gigantea
F Sugawara1, Y F Hallock2, G D Bunkers3
1a The Institute of Physical and Chemical Research (RIKEN) , Wako , Saitama 351-01 , Japan.
Abstract:
Phytoactive substances were present in a culture broth of Drechslera gigantea, a pathogenic fungus of several grasses. Twelve eremophilane sesquiterpenes (1, 2, 3, 4, 6, 7, 10, 11, 12, 13, 14, and 15) were isolated and structurally characterized by a combination of single-crystal X-ray diffraction and spectroscopic analyses. Most of these sesquiterpenoids were phytotoxic; however, compounds 1 and 3 caused chlorophyll retention, an activity previously associated with phytohormones.
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