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1Istituto di Discipline Otorinolaringologiche, Università degli Studi di Siena, Viale Bracci, 53100, Siena, Italy.
Italian Journal of Neurological Sciences
|June 18, 2016
Summary
Headache impacts 80% of people annually. This review explores primary headache pathophysiology, linking allergic rhinitis in children to nasal dysfunction and resultant headaches.
Area of Science:
- Neurology
- Immunology
- Otolaryngology
Context:
- Headaches are a prevalent health concern, affecting a large portion of the global population annually.
- Primary headaches, including rhinogenic headache, involve complex neurovascular mechanisms.
- Allergic rhinitis is a common condition in children, often associated with nasal symptoms.
Purpose:
- To review current theories on the neurovascular pathophysiology of primary headaches, focusing on rhinogenic headache.
- To investigate the relationship between allergic rhinitis and headache in a pediatric population.
- To explore the potential role of nasal dysfunction in headaches associated with allergic rhinitis.
Summary:
- This work reviews emerging theories on the neurovascular pathophysiology of primary headaches, with a specific emphasis on rhinogenic headache.
- A study of 2262 primary school children examined the link between allergic rhinitis and headaches.
- Findings suggest that headaches in allergic patients are consistently associated with underlying nasal dysfunction.
Impact:
- Provides updated insights into the pathophysiology of primary headaches, particularly rhinogenic types.
- Highlights a significant association between allergic rhinitis, nasal dysfunction, and headaches in children.
- Suggests potential therapeutic targets for managing headaches in allergic individuals by addressing nasal dysfunction.

