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Bile acids in bile after monensin treatment
1Institute of General Pathology, University of Genoa, Italy.
Experimental Pathology
|January 1, 1989
Abstract:
Bile derived from monensin treated bile-fistula rats has been analysed for bile acids content. Bile flow and bile acids decrease in bile following monensin treatment, in agreement with the disruption of the Na+ gradient determined by the ionophore and necessary for the vectorial Na+-cotransport of taurocholate at the sinusoidal pole of the hepatocyte.