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Related Experiment Videos

[Recurrent avascular bone necrosis in systemic lupus].

M Abu-Shakra, S Sukenik, Y Shoenfeld

    Harefuah
    |February 15, 1989
    PubMed
    Summary

    Aseptic necrosis, a bone condition, often occurs in patients with systemic lupus erythematosus (SLE) during corticosteroid treatment. This case highlights its occurrence in the shoulders, a less common site, emphasizing the need for vigilance.

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    Area of Science:

    • Rheumatology
    • Orthopedics
    • Internal Medicine

    Background:

    • Systemic lupus erythematosus (SLE) is a chronic autoimmune disease.
    • Corticosteroid therapy is a cornerstone in managing SLE but is associated with potential complications.
    • Ischemic bone necrosis, also known as avascular necrosis, is a recognized complication, frequently affecting the hip.

    Observation:

    • A 21-year-old male diagnosed with SLE presented with bilateral shoulder pain.
    • The patient had a history of SLE involving skin, joints, brain, small intestine, and kidneys, and was undergoing corticosteroid treatment.
    • He previously experienced severe knee pain, diagnosed as aseptic necrosis of the femur and tibia via bone scan.

    Findings:

    • The patient developed bilateral shoulder pain with limited range of motion.
    • Radiographic examination confirmed bilateral ischemic necrosis of the shoulder joints.
    • This presentation is notable as shoulder involvement is less common than hip necrosis in SLE patients on corticosteroids.

    Implications:

    • Aseptic necrosis should be strongly suspected in SLE patients experiencing arthralgia, particularly during corticosteroid therapy.
    • Early recognition and diagnosis of bone necrosis are crucial for appropriate management and preventing further joint damage.
    • This case underscores the importance of considering less common sites of ischemic necrosis in SLE patients.

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