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Apparent spontaneous regression of malignant neoplasms after radiography: Report of four cases
Jun Sasaki1, Hideo Kurihara1, Yoshishige Nakano1
1Kurihara Thyroid Clinic, Iwate, Japan.
Introduction:
On rare occasions, an apparently spontaneous regression of unknown etiology is observed in a neoplasm. We report a series of 4 patients with apparent spontaneous regression of malignant lymphomas after radiography.
Presentation Of Case:
All four of the tumors were malignant lymphomas. The regressions occurred between 1 and 2 months after the radiographic examinations. All four patients later underwent relapse and needed additional treatments: surgery, chemotherapy and/or radiation.
Discusssion:
Four cases had the following features in common: (1) the neoplasms were radiosensitive, (2) the regression occurred after radiography, (3) none of the neoplasms was in the advanced stage, and (4) the doses received through radiographic exposure were a little higher than usual because CT was included for most of the patients.
Conclusion:
We suspect that the apparently spontaneous regression of malignant lymphomas was caused by the small radiation doses received in the radiographic examinations.
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