Management of catheter-associated upper extremity deep venous thrombosis

Jeffrey D Crawford1, Timothy K Liem1, Gregory L Moneta1

  • 1Division of Vascular Surgery, Department of Surgery, Oregon Health and Science University, Portland, Ore.

Insights

Central venous catheters increase the risk of upper extremity deep venous thrombosis (UEDVT). This review covers catheter-associated UEDVT, focusing on risk factors, diagnosis, prevention, and management strategies.

Area of Science:

  • Vascular Medicine
  • Thrombosis Research
  • Medical Device Complications

Background:

  • Central venous catheters (CVCs) and peripherally inserted central catheters (PICCs) are significant risk factors for upper extremity deep venous thrombosis (UEDVT).
  • While literature on catheter-associated (CA) UEDVT has grown, robust evidence for clinical application in screening, diagnosis, prevention, and treatment remains limited.

Purpose of the Study:

  • To review current evidence on catheter-associated upper extremity deep venous thrombosis (CA-UEDVT) applicable to clinical practice.
  • To consolidate information on CA-UEDVT, including anatomy, risk factors, diagnostic methods, and management.

Main Methods:

  • Literature review of current evidence on CA-UEDVT.
  • Focus on clinically applicable findings related to risk, diagnosis, and management.

Main Results:

  • Central venous catheters are identified as major risk factors for UEDVT.
  • Duplex ultrasound is highlighted as the preferred diagnostic modality for CA-UEDVT.
  • Preventive strategies and a management algorithm for CA-UEDVT are discussed.

Conclusions:

  • Limited strong evidence exists for screening, diagnosis, prevention, and treatment of CA-UEDVT.
  • A comprehensive review of CA-UEDVT, including risk factors and management, is presented to guide clinical practice.

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