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Accuracy of a Flash Glucose Monitoring System in Diabetic Dogs
S Corradini1, B Pilosio1, F Dondi1
1Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia, Italy.
Journal of Veterinary Internal Medicine
|June 20, 2016
Summary
This study found that the FreeStyle Libre flash glucose monitoring system (FGMS) is accurate and easy to use for measuring interstitial glucose in diabetic dogs. The system demonstrated good correlation with plasma glucose levels, proving effective for canine diabetes management.
Area of Science:
- Veterinary Medicine
- Endocrinology
- Medical Devices
Background:
- A novel flash glucose monitoring system (FGMS) was developed for human use.
- This system continuously measures interstitial glucose (IG) for 14 days.
Purpose of the Study:
- To evaluate the clinical and analytical accuracy of the FGMS in diabetic dogs.
- To assess the feasibility of using FGMS for long-term glucose monitoring in canine patients.
Main Methods:
- A prospective, observational study involving ten client-owned diabetic dogs on insulin therapy.
- The FGMS was applied to the dogs' necks for up to 14 days.
- Interstital glucose measurements were compared against plasma glucose concentrations analyzed by a hexokinase-based reference method on days 1-2, 6-7, and 13-14.
Main Results:
- The FGMS was well-tolerated, painless, and easy to apply in all dogs, with mild erythema noted in 50% of cases.
- A strong correlation (rho = 0.94; P < .001) was observed between IG and plasma glucose (PG) concentrations.
- The FGMS achieved 93%, 99%, and 99% accuracy at low, normal, and high glucose concentrations, respectively.
Conclusions:
- The FGMS is a user-friendly and accurate tool for interstitial glucose monitoring in diabetic dogs.
- This technology offers a promising option for managing canine diabetes mellitus.

