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Accuracy of a Flash Glucose Monitoring System in Diabetic Dogs
S Corradini1, B Pilosio1, F Dondi1
1Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia, Italy.
Background:
A novel flash glucose monitoring system (FGMS) (FreeStyle Libre, Abbott, UK) was recently developed for humans. It continuously measures the interstitial glucose (IG) concentrations for 14 days.
Objectives:
To assess the clinical and analytical accuracy of the FGMS in diabetic dogs.
Animals:
Ten client-owned diabetic dogs on insulin treatment.
Methods:
Prospective and observational study. The FGMS was placed on the neck for up to 14 days. During the 1st-2nd, 6-7th, and 13-14th days from application, the IG measurements were compared with the plasma (EDTA) glucose (PG) concentrations analyzed by a reference hexokinase based method.
Results:
The application and the use of the FGMS were apparently painless, easy, and well tolerated by all dogs. Mild erythema at the site of the application was found in 5/10 dogs at the end of the wearing period. A good correlation between IG and PG concentrations (rho = 0.94; P < .001) was found. The FGMS was 93, 99, and 99% accurate at low, normal, and high blood glucose concentrations. Mean ± standard deviation difference from the reference method was 2.3 ± 46.8 mg/dL.
Conclusion And Clinical Importance:
The FGMS is easy to use and is accurate for IG glucose measurement in diabetic dogs.
