[Investigation and analysis for impact factors of distress in patients with first diagnosed lung cancer]

To study the impact factors of psychological distress in patients with first diagnosed lung cancer.

The cross-sectional study was applied to newly diagnosed lung cancer patients who received treatments in Cancer Center of West China Hospital of Sichuan University in Chengdu from June 2013 to March 2015 by distributed questionnaires. The general information of the patients, the hospital anxiety and depression scale (HADS) and distress management screening measure (DMSM) were included in the questionnaire to evaluate the states of distress, pain and the factors related to the distress of the patients.

The survey investigated a total of 390 patients with first diagnosed lung cancer, including 291 male patients and 99 female patients. The proportion of the patients with positive anxiety symptom was 26.7% (104/390), with positive depression symptom was 27.7% (108/390), and with positive distress symptom was 30.0% (117/390). On the top five problem list of DMSM were worry, disease treatment, breathing, pain and sleep. The Spearman correlation analysis showed that anxiety score, depression score, and the pain intensity were positively correlated with the distress. Multiple linear regression analysis showed that gender (β=-0.209, P=0.003), age (β=-0.098, P=0.042), chronic disease (β=0.378, P<0.001), and pain score (β=0.100, P=0.029) could affect the distress of the patients. Smoking (β=0.111, P=0.041) could affect the anxiety of newly diagnosed lung cancer patients.

The gender, age, chronic disease and pain score of the patients are the independent factors of the psychological distress of first diagnosed lung cancer patients. Smoking is the predictive factors of the patients with anxiety. Controlling the pain intensity and the clinical process of chronic disease of the patients actively, solving the sleep and breathing problem and helping the patients to quit smoking progressively could alleviate the psychological distress of the patients.