Related Experiment Video
Updated: Mar 19, 2026

09:54
Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models
Published on: December 3, 2019
10.8K
Supravenous Hyperpigmentation in an HIV-Infected Patient
Janet Gilmour1, Duane Bates2, Genevieve Olsen3
1Southern Alberta HIV/AIDS Clinic, Alberta Health Services, Calgary, Alberta, Canada; gilmourj@ucalgary.ca.
Skinmed
|June 21, 2016
Summary
This case highlights the complex health needs of a long-term human immunodeficiency virus (HIV) patient. It details managing multiple comorbidities alongside chronic HIV infection.
Area of Science:
- Internal Medicine
- Infectious Diseases
- Hematology
Background:
- Routine follow-up for a 47-year-old African American male with a 24-year history of human immunodeficiency virus (HIV).
- Patient presents with a complex medical history requiring comprehensive management.
Observation:
- The patient has a history of insomnia, gastroesophageal reflux disease, and pulmonary embolism.
- Additional conditions include right shoulder musculoskeletal pain, latent tuberculosis infection, and sickle cell trait (hemoglobin S variant).
Findings:
- The case underscores the multifaceted health challenges faced by individuals with long-standing HIV infection.
- Co-management of HIV with other chronic conditions is essential for patient well-being.
Implications:
- This case emphasizes the need for integrated care models in managing patients with HIV and multiple comorbidities.
- Understanding the interplay of various health conditions is crucial for optimizing treatment strategies and patient outcomes in long-term HIV care.
Related Concept Videos
Changes in Skin Color: Clinical Perspectives
4.1K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
4.1K
Pulmonary Tuberculosis I
1.2K
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
1.2K
Pigmentation
4.9K
The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
4.9K
Immunodeficiency Diseases
2.7K
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
There are three main causes of immunodeficiency...
2.7K

