Related Experiment Video
Updated: Mar 19, 2026
Breath Collection from Children for Disease Biomarker Discovery
Published on: February 14, 2019
The impact of severe lung disease on evidential breath analysis collection
Leigh M Seccombe1, Peter G Rogers2, Lachlan Buddle2
1Thoracic Medicine, Concord Repatriation General Hospital, Concord, NSW 2139, Australia; Sydney Medical School, Sydney University, Camperdown, NSW 2050, Australia.
Background:
It is a legal requirement to supply a breath analysis sample when requested by Police at roadside checkpoints. The current device requires a 1L sample at 8L·min(-1). Court disputes commonly attribute respiratory disease for failure to produce a sample.
Objective:
To determine whether respiratory disease aetiology and/or severity precludes an adequate breath sample using a modern evidential breath analyser.
Methods:
Subjects performed breath analysis following standard Police procedure. Three efforts within 15min were allowed and any reasons for failure recorded.
Results:
24 subjects with interstitial lung disease (ILD) and 26 subjects with chronic obstructive pulmonary disease (COPD) were studied and met minimum respiratory function criteria as per device specifications. 18 ILD subjects (75%) and 24 COPD subjects (92%) were able to provide a sample. All subjects with a vital capacity below 1.5L were unable to provide a sample.
Discussion:
In the balance of probabilities most patients with lung disease are able to supply an evidential breath sample. The exception is a very severe disease, particularly in volume limited patients.
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