[Multiple off pump coronary artery bypass grafting - risks and benefits]

Avoidance of extracorporeal circulation during beating heart surgery (OP CAB = Off-Pump Coronary Artery Bypass Surgery) for aortocoronary bypass grafting (ACBG) is gaining increasing importance in modern cardiac surgery. With the development of new mechanical stabilization devices, the revascularization of the posterior wall of the heart and the distal rith coronary artery became feasable. Especially high-risk patients with multiple risk factors for open heart surgery will profit from this approach, because the negative effects of the extracorporeal circulation are avoided.

From 7/97 until 12/99 a total of 158 patients with ultivessel-coronary artery disease were operated on the beating heart. In the same time course, a total of 2869 patients were operated conventionally using the extracorporeal circulation as a standard procedure.

Due to patient selection, the two groups differ in the preoperative data concerning previous neurologic deficits. None of the patients in th OP CAB group suffered a permanent neurologic deficit after the operation, whereas in the CAB group the rate of stroke was 1.3%. The rate of temporary neurologic deficits, such as TIA (temporary ischemic attack) or PRIND (prolonged reversible neurologic deficit), was higher in the OP CAB group due to patient selection. No surgially associated aortic dissection was seen in the OP CAB group.

This and other studies have shown the effectiveness of OP CAB surgery concerning perioperative complications and survival rates. Especially high-risk patients with multiple risk factors for a cardiac operation profit from a beating-heart operation avoiding extracorporeal circulation. The question in how far the higher rate of reoccuring angina and the larger number of interventional treatments in OP CAB patients reported in the literature are due to the learning curve remains unanswered. Long-term studies will show whether the result of beating heart surgery is as good as the result of conventional "on-bypass" surgery.