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Published on: June 2, 2022
Warfarin-induced calciphylaxis in patients with normal renal function
L Huilaja1,2, M Turpeinen3,4, H Tokola5,6
1Department of Dermatology, Oulu University Hospital, Oulu, Finland.
What Is Known And Objective:
Calciphylaxis is a rare and potentially life-threatening cause of skin necrosis and is poorly recognized by clinicians in non-uraemic patients.
Case Description:
We report five cases of warfarin-induced calciphylaxis in patients with normal renal function. In four cases, sodium thiosulphate was successfully used as a treatment. No other predisposing factors besides obesity and warfarin were found in these patients.
What Is New And Conclusion:
Previously only few cases of solely warfarin-induced calciphylaxis have been described. Treatment with sodium thiosulphate has shown promising results, and there is thus a need to improve the recognition of calciphylaxis.
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