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Persistence with medication and overactive bladder: an ongoing challenge.

Adrian Wagg1

  • 1a Department of Medicine , University of Alberta , Edmonton , AB , Canada.

Expert Review of Pharmacoeconomics & Outcomes Research
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PubMed
Summary
This summary is machine-generated.

Improving overactive bladder treatment requires better medication adherence and persistence. This review explores modifiable factors to enhance patient outcomes in managing this chronic condition.

Keywords:
Overactive bladderadherencepersistencetreatment outcomesurgency incontinence

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Area of Science:

  • Pharmacology
  • Urology
  • Chronic Disease Management

Background:

  • Optimal overactive bladder (OAB) management necessitates patient adherence to prescribed medications.
  • Low adherence and persistence rates compromise OAB treatment efficacy, leading to suboptimal outcomes and disease progression.

Purpose of the Study:

  • To review current knowledge on adherence and persistence in OAB treatment.
  • To identify modifiable factors, drawing from other chronic conditions, to improve adherence and persistence in OAB management.

Main Methods:

  • A narrative review approach was employed.
  • A structured PubMed search utilized terms including persistence, adherence, overactive bladder, urgency incontinence, and chronic conditions.
  • The review incorporated emerging themes from existing data and expert commentary.

Main Results:

  • Adherence to OAB medications has historically been suboptimal.
  • There is a limited understanding of the specific modifiable factors contributing to poor adherence in OAB.
  • Strategies tested in other chronic disease areas may be adaptable for OAB.

Conclusions:

  • Enhanced understanding of OAB pathophysiology can inform adherence improvement strategies.
  • Implementing evidence-based strategies from other fields holds potential to improve OAB treatment adherence and persistence.
  • Addressing modifiable factors is crucial for optimizing pharmacological management of OAB.