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Updated: Mar 19, 2026

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
Published on: January 26, 2024
Preeclampsia and preterm delivery: A population-based case-control study
Emma L Davies1, Jacqueline S Bell1,2, Sohinee Bhattacharya3
1a Public Health, Summerfield House , NHS Grampian , Aberdeen , Scotland , UK.
Objective:
To determine the contribution of preeclampsia toward preterm birth in primiparous women.
Methods:
This large population-based case-control study used the Aberdeen Maternity and Neonatal Databank to analyze data on primiparous women with singleton pregnancies, who delivered between 1997 and 2012.
Results:
A significant positive association was found between preeclampsia and preterm birth (adjusted odds ratio 4.43; 95% confidence interval 3.80-5.16). Magnitude of association varied according to the onset of delivery and year of delivery.
Conclusion:
Preeclampsia is an important contributor to preterm delivery in this setting and therefore a potentially useful condition to target in order to reduce preterm rates.
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