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Published on: March 30, 2015
Cost-effectiveness of Management Options for Small Renal Mass: A Systematic Review
Ye Wang1, Yu-Wei Chen, Jeffrey J Leow
1*Center for Surgery and Public Health, Brigham and Women's Hospital, Harvard Medical School †Harvard School of Public Health §Division of Urology, Brigham and Women's Hospital, Boston, MA ‡College of Physicians and Surgeons, Columbia University, New York City, NY.
For small renal masses (SRMs), ablation is more cost-effective than surgery. Laparoscopic partial nephrectomy is also cost-effective compared to open surgery, with renal mass biopsy being cost-effective in the US.
Area of Science:
- Urology
- Health Economics
- Oncology
Background:
- Small renal masses (SRMs) present significant management challenges due to high surgical costs.
- Evaluating the economic impact of different treatment strategies is crucial for optimal resource allocation.
Purpose of the Study:
- To systematically review and evaluate the cost-effectiveness of various management options for SRMs.
- To synthesize existing economic evidence to guide clinical and policy decisions.
Main Methods:
- A comprehensive systematic literature search was conducted across six databases (inception to August 2015).
- Inclusion criteria focused on full economic evaluations of SRM management options published in English.
- Six studies met the inclusion criteria for analysis.
Main Results:
- Ablation therapy was found to be more cost-effective than nephron-sparing surgery for SRMs.
- Laparoscopic partial nephrectomy demonstrated superior cost-effectiveness compared to the open surgical approach.
- Renal mass biopsy was cost-effective for immediate treatment in the United States, but not in Canada.
Conclusions:
- Current evidence suggests that ablation and laparoscopic partial nephrectomy are cost-effective management strategies for SRMs.
- Geographical variations exist in the cost-effectiveness of renal mass biopsy.
- Further research, including international cost-effectiveness analyses, is recommended to address knowledge gaps.
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