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Related Experiment Video

Updated: Mar 19, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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[Migraine with visual aura].

S Bidot1, D Biotti2

  • 1Fondation ophtalmologique Adolphe-de-Rothschild, 25, rue Manin, 75019 Paris, France; Centre hospitalier national d'ophtalmologie des Quinze-Vingts, 28, rue de Charenton, 75012 Paris, France.

Journal Francais D'Ophtalmologie
|June 22, 2016
PubMed
Summary

Migraine with visual aura involves temporary visual disturbances, potentially caused by cortical spreading depression. Treatment focuses on rapid pain relief and reducing episode frequency.

Keywords:
AuraCéphaléeFortification spectrumHeadachesMigraineScotome scintillantTransient visual disturbanceTrouble visuel transitoire

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Area of Science:

  • Neurology
  • Ophthalmology

Background:

  • Migraine with visual aura presents as recurrent transient visual disturbances preceding headaches.
  • The exact pathophysiology remains unclear, but cortical spreading depression is a leading hypothesis.
  • Visual auras encompass a range of phenomena, from simple to complex visual disturbances.

Purpose of the Study:

  • To summarize the understanding of migraine with visual aura.
  • To highlight diagnostic criteria and treatment goals.

Main Methods:

  • Review of existing literature and diagnostic criteria.
  • Synthesis of current knowledge on pathophysiology and symptoms.

Main Results:

  • Visual auras may stem from cortical spreading depression, initiating trigemino-vascular activation.
  • The "fortification spectrum" is a characteristic visual symptom.
  • Diagnosis relies on the International Classification of Headache Disorders (2013).

Conclusions:

  • Migraine with visual aura requires effective pain management and preventative strategies.
  • Further research into pathophysiology may yield improved therapeutic approaches.