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Published on: June 20, 2025
Inflammation and the Silent Sequelae of Stroke
1University of Washington School of Medicine, Seattle, WA, USA. kjb@uw.edu.
Abstract:
Depression and fatigue are common after stroke and negatively impact the quality of life of stroke survivors. The biological bases of these symptoms are unknown, but an abundance of data point to a role for inflammation. This review highlights evidence supporting the contribution of inflammation to poststroke depression and poststroke fatigue. Potential treatments for poststroke depression and poststroke fatigue are explored, with a special emphasis on those that modulate the immune response.
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