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Updated: Mar 19, 2026

Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach
Published on: January 24, 2018
No differences between fixed- and mobile-bearing total knee arthroplasty.
B L Fransen1, D C van Duijvenbode2, M J M Hoozemans2,3
1CORAL - Centre for Orthopaedic Research Alkmaar, Department of Orthopaedics, Medical Centre Alkmaar, Wilhelminalaan 12, 1815 JD, Alkmaar, The Netherlands. b.l.fransen@mca.nl.
This comprehensive review found no significant differences between mobile-bearing total knee arthroplasty (MB-TKA) and fixed-bearing total knee arthroplasty (FB-TKA) in terms of wear, loosening, survival, or clinical outcomes for knee osteoarthritis.
Area of Science:
- Orthopedic Surgery
- Biomedical Engineering
- Knee Arthroplasty Research
Background:
- The choice between mobile-bearing total knee arthroplasty (MB-TKA) and fixed-bearing total knee arthroplasty (FB-TKA) remains a subject of ongoing debate in orthopedic surgery.
- Previous reviews have often concentrated on a limited number of randomized controlled trials, potentially overlooking valuable data from smaller studies.
Purpose of the Study:
- To conduct a comprehensive literature review comparing mobile-bearing total knee arthroplasty (MB-TKA) and fixed-bearing total knee arthroplasty (FB-TKA).
- To evaluate all available studies examining insert wear, prosthesis loosening, survival rates, and clinical outcomes for both MB-TKA and FB-TKA in treating knee osteoarthritis.
Main Methods:
- An extensive literature search was conducted using the PubMed database.
- Included studies were those that directly compared MB-TKA and FB-TKA and assessed at least one of the following: insert wear, signs of loosening, prosthesis survival rate, or clinical outcome.
- The review encompassed meta-analyses, systematic reviews, randomized controlled trials, comparative studies, and bilateral TKA studies.
Main Results:
- A total of 127 studies were included after an initial screening of 258 articles.
- The aggregated results from all included study types indicated a lack of significant difference between MB-TKA and FB-TKA.
- No discernible variations were found in insert wear, risk of loosening, survivorship, or clinical outcomes between the two bearing designs.
Conclusions:
- This comprehensive review of all available literature, including diverse study types, found no significant differences between MB-TKA and FB-TKA.
- The findings suggest that insert wear, loosening, survivorship, and clinical outcomes are comparable for both mobile-bearing and fixed-bearing designs.
- The selection between MB-TKA and FB-TKA in clinical practice should be guided by surgeon experience and judgment due to the absence of clear scientific evidence favoring one design over the other.
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