Epidemiology and Challenges to the Management of Advanced CKD

Azzour D Hazzan1, Candice Halinski1, Sofia Agoritsas1

  • 1SB Division of Nephrology, Department of Medicone, Hofstra Northwell School of Medicine, Great Neck, NY; and Division of Nephrology, Lenox Hill Hospital, New York, NY.

Insights

Advanced chronic kidney disease (CKD) care requires different strategies as kidney function declines. Optimal management during advanced CKD is crucial for better transitions to end-stage renal disease (ESRD).

Area of Science:

  • Nephrology
  • Internal Medicine
  • Public Health

Background:

  • Advanced chronic kidney disease (CKD) presents unique treatment challenges.
  • Kidney function decline necessitates planning for renal replacement therapy.
  • Effective management in advanced CKD improves outcomes for end-stage renal disease (ESRD).

Purpose of the Study:

  • To review definitions and epidemiology of advanced CKD.
  • To discuss the outcomes associated with advanced CKD.
  • To highlight barriers to optimal advanced CKD care.

Main Methods:

  • Literature review of advanced CKD definitions.
  • Analysis of epidemiological data for advanced CKD.
  • Examination of outcomes and care barriers in advanced CKD.

Main Results:

  • Advanced CKD is characterized by distinct treatment goals.
  • Substantial barriers impede optimal care for advanced CKD patients.
  • Understanding epidemiology and outcomes is key for improved patient management.

Conclusions:

  • Successful management of advanced CKD is vital for patient outcomes.
  • Addressing care barriers can enhance transitions to ESRD.
  • Further research into advanced CKD definitions and epidemiology is warranted.

Related Concept Videos

Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
586
Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
1000
Chronic Kidney Disease IV: Nursing Management01:18

Chronic Kidney Disease IV: Nursing Management

Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care​.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
559
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
891
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
450
Nephrotic Syndrome III : Nursing Management01:24

Nephrotic Syndrome III : Nursing Management

Nursing management for nephrotic syndrome adapts as the disease progresses, with strategies evolving to address advancing symptoms and complications.Early-Stage Management In the early stages, nursing interventions for nephrotic syndrome resemble those used in managing acute glomerulonephritis, focusing on symptom monitoring, fluid balance, and managing mild to moderate edema.Vital Signs: Regularly monitor blood pressure, pulse, respiratory rate, and temperature to promptly identify...
421