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Related Experiment Video

Updated: Mar 19, 2026

Iris Fixation via External Pentagram Suturing

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

[Fusarium keratitis with dramatic outcome].

J Lübke¹, C Auw-Hädrich², T Meyer-Ter-Vehn³

¹Klinik für Augenheilkunde, Universitätsklinikum Freiburg im Breisgau, Killianstr. 5, 79106, Freiburg, Deutschland. jan.luebke@uniklinik-freiburg.de.

Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft

|June 22, 2016

Summary

This summary is machine-generated.

Early antifungal therapy is crucial for fungal keratitis. This case highlights that even with treatment, resistant Fusarium infections can lead to severe outcomes like endophthalmitis and necessitate eye removal.

Keywords:

Contact lenses Endophthalmitis Enucleation Fusarium Keratitis

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Area of Science:

Ophthalmology
Mycology

Background:

Fungal keratitis is a rare but serious eye infection, more prevalent in Asia than Europe.
Treatment options include topical and systemic antifungal therapy, with surgery for advanced cases.

Observation:

A 60-year-old woman developed Fusarium keratitis and subsequent endophthalmitis after contact lens wear.
The infection exhibited resistance to multiple antimycotic drugs, leading to enucleation to prevent systemic spread.

Findings:

Histopathology revealed significant inflammation but no detectable Fusarium, suggesting immune overreaction post-treatment.
Clinical presentation strongly indicated fungal infection despite negative histological findings.

Implications:

Prompt initiation of antimycotic therapy is vital for suspected fungal keratitis.
Even with early intervention, highly resistant fungal pathogens may result in irreversible vision loss and necessitate globe removal.