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Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis
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Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis

Published on: July 4, 2007

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Post-traumatic acute disseminated encephalomyelitis

Dali Magazi, Lezanne Wynand-Ndlovu, Patrick Legwara

    Radiology Case Reports
    |June 22, 2016
    PubMed

    Insights

    A soccer tackle caused blindness from optic neuritis in a young man, with brain imaging suggesting acute disseminated encephalomyelitis (ADEM). This case explores ADEM as a potential post-traumatic event.

    Area of Science:

    • Neurology
    • Neuroimmunology
    • Trauma Neurology

    Background:

    • Acute disseminated encephalomyelitis (ADEM) is an immune-mediated inflammatory demyelinating disease of the central nervous system.
    • ADEM typically follows an infection or vaccination, but its association with trauma is less understood.

    Observation:

    • A 23-year-old male experienced sudden blindness due to optic neuritis after a head injury sustained during a soccer match.
    • Brain MRI revealed white-matter changes consistent with ADEM.
    • MR spectroscopy indicated a demyelination pattern.

    Findings:

    • The clinical presentation and neuroimaging findings strongly suggest ADEM.
    • The temporal association between head trauma and the onset of ADEM raises questions about a potential post-traumatic etiology.

    Implications:

    • This case highlights the possibility of acute disseminated encephalomyelitis (ADEM) occurring subsequent to head trauma.
    • It prompts further investigation into the role of trauma as a trigger for ADEM.
    • Understanding this association is crucial for accurate diagnosis and management of neurological conditions following injury.
    Keywords:
    ADEM, acute disseminated encephalomyelitisMRI, magnetic resonance imaging

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