Related Experiment Video
Updated: Mar 19, 2026

Isolation of mRNAs Associated with Yeast Mitochondria to Study Mechanisms of Localized Translation
Published on: March 14, 2014
Nucleus to Mitochondria: Lost in Transcription, Found in Translation
Julie St-Pierre1, Ivan Topisirovic2
1Goodman Cancer Research Centre, McGill University, Montréal, QC H3A 1A3, Canada; Department of Biochemistry, McGill University, Montreal, QC H3A 1A3, Canada.
Abstract:
Mitochondrial genes reside in the nucleus and mitochondria. In a recent paper in Nature, Couvillion et al. (2016) describe their development of a "mitoribosome profiling" approach and demonstrate that changes in expression of nuclear- and mitochondrial-encoded genes are coordinated at the level of translation during metabolic adaptation to fuel source changes.
More Related Videos
09:53Author Spotlight: Advancing Techniques and Discoveries in Protein Synthesis and Assembly Through Innovative Mitochondrial Research
Published on: June 7, 2024
08:33Labelling and Visualization of Mitochondrial Genome Expression Products in Baker's Yeast Saccharomyces cerevisiae
Published on: April 11, 2021
Related Concept Videos
Regulated mRNA Transport
Regulated mRNA Transport
The Nucleolus
The Nucleolus
Translation in Prokaryotes
Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of...