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Published on: July 13, 2009
Permeability of protective gloves to sodium lauryl sulfate. Release chambers used as an in vitro test system
1Department of Dermatology, Gentofte Hospital, University of Copenhagen, DenmarkDepartment of Dermatological Research, Leo Pharmaceutical Products, Denmark.
Background/Aims:
Gloves are important and necessary in many occupations especially in wet work. They may offer a protection against harmful materials, but many substances may also penetrate protective gloves.
Methods:
The permeability of 6 different commonly used protective gloves to the anionic detergent sodium lauryl sulfate (SLS) was investigated. The gloves were tested as membranes in diffusion cells at 32°C. ((35) S)SLS 1% was used as permeant and synthetic sweat was used as recipient. Samples were counted on a scintillation counter.
Results:
During a test period of 24 h, none of the gloves tested were found to be permeable to SLS.
Conclusions:
The gloves tested were found to offer protection against SLS. The difussion cells were useful for in vitro testing of protective gloves under controlled experimental conditions.
