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Related Experiment Video

Updated: Mar 19, 2026

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
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In vivo skin relief measurement using a new optical profilometer.

A D Potorac1, I Toma1, J Mignot1

  • 1lStr Universitatii 1, University of Suceava, 5800 Suceava, Romania2Laboratoire de Métrologie des interfaces, lnstitut Universitaire de Technologie, 25009 Besancon Cedex, France.

Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [And] International Society for Digital Imaging of Skin (ISDIS) [And] International Society for Skin Imaging (ISSI)
|June 22, 2016
PubMed
Summary

A novel non-contact optical triangulation profilometer enables direct in vivo skin topography measurement. This advanced skin analysis technique offers high-speed data acquisition, improving diagnostic capabilities.

Keywords:
Skin surfacefurrowslaser beamprofilometrytopographytriangulation methodwrinkles

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Area of Science:

  • Biomedical Engineering
  • Dermatology
  • Optical Physics

Background:

  • Traditional skin topography assessment relies on 2D profilometry with physical replicas.
  • In vivo measurement of skin surface characteristics is challenging with existing methods.

Purpose of the Study:

  • To develop a novel non-contact profilometer for direct in vivo skin topography quantification.
  • To overcome limitations of replica-based methods for skin surface analysis.

Main Methods:

  • A new profilometer was engineered utilizing an optical triangulation principle.
  • The system employs a position sensing detector to analyze reflected laser light from the skin surface.

Main Results:

  • The developed profilometer allows for direct in vivo measurement of skin topography.
  • High-speed data acquisition is achievable with the non-contact optical system.

Conclusions:

  • Non-contact optical triangulation offers a high-speed method for skin topography assessment.
  • The system effectively minimizes laser beam enlargement effects caused by skin absorption, enhancing measurement accuracy.