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Where are oncofertility and fertility preservation treatments heading in 2016?

Miyuki Harada1, Yutaka Osuga1

  • 1Department of Obstetrics & Gynecology, Faculty of Medicine, University of Tokyo, 7-3-1, Hongo, Bunkyo, Tokyo, 113-8655, Japan.

Future Oncology (London, England)
|June 23, 2016
PubMed

Insights

Cancer survival is up, boosting fertility preservation needs. This review examines current options and future fertility preservation strategies, highlighting evidence limitations.

Area of Science:

  • Reproductive Medicine
  • Oncology
  • Cell Biology

Background:

  • Improved cancer survival rates increase the need for fertility preservation.
  • Advancements in assisted reproductive technologies support oncofertility.
  • Fertility preservation is crucial for cancer patients of reproductive age.

Purpose of the Study:

  • To review current fertility preservation methods for cancer patients.
  • To discuss limitations and evidence gaps in existing strategies.
  • To propose future directions for oncofertility research and treatment.

Main Methods:

  • Literature review of oncofertility and fertility preservation.
  • Analysis of available and emerging fertility preservation techniques.
  • Discussion of clinical concerns and future research needs.

Main Results:

  • Several fertility preservation options exist, but evidence is limited for each.
  • Current methods include oocyte, embryo, and ovarian tissue cryopreservation.
  • Emerging techniques show promise but require further validation.

Conclusions:

  • Fertility preservation is advancing, but evidence gaps remain a concern.
  • Further research is needed to validate emerging oncofertility strategies.
  • Future approaches may offer improved options for cancer patients.
Keywords:
drug delivery systemsfertility preservationin vitro follicle growthin vitro sperm developmentoncofertilityoocyte cryopreservationovarian protectionovarian tissue cryopreservationuterine transplantation

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