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Updated: Mar 19, 2026
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Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
Published on: March 25, 2022
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International collaborative study on EUS-guided gallbladder drainage: Are we ready for prime time?
Michel Kahaleh1, Manuel Perez-Miranda2, Everson L Artifon3
1Division of Gastroenterology and Hepatology, Weill Cornell Medical College, New York, NY, United States.
Summary
Endoscopic ultrasound-guided transmural gallbladder drainage (EUS-GBD) is a feasible and safe treatment for cholecystitis, showing high success rates in international patient cohorts. Further research is needed to optimize techniques.
Area of Science:
- Gastroenterology
- Interventional Endoscopy
- Surgical Oncology
Background:
- Cholecystectomy is the standard treatment for cholecystitis.
- Transpapillary gallbladder drainage is an endoscopic option.
- Endoscopic ultrasound-guided transmural drainage of the gallbladder (EUS-GBD) is an emerging technique.
Purpose of the Study:
- To report the cumulative international experience with EUS-GBD.
- To evaluate the feasibility, safety, and efficacy of EUS-GBD.
Main Methods:
- A registry captured EUS-GBD cases from January 2012 to November 2013 across 3 institutions.
- Data included patient demographics, disease characteristics, and procedural/clinical outcomes.
- Follow-up assessed technical and clinical success, and adverse events.
Main Results:
- 35 patients (15 malignant, 20 benign) with a median age of 81 underwent EUS-GBD.
- Technical success was 91.4%, with a long-term clinical success rate of 89%.
- Immediate adverse events occurred in 14% and delayed in 11%; stent type and puncture site did not impact outcomes.
Conclusions:
- EUS-GBD demonstrates feasibility, safety, and effectiveness for cholecystitis treatment.
- Prospective studies are recommended to confirm findings and refine techniques.
- EUS-GBD offers a viable endoscopic alternative for gallbladder drainage.
