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Paediatric nasal polyps in cystic fibrosis

Mohd Afiq Mohd Slim1, David Dick1, Keith Trimble1

  • 1Department of Ear, Nose and Throat, Royal Victoria Hospital, Belfast, UK.

BMJ Case Reports
|June 23, 2016
PubMed

Insights

Cystic fibrosis (CF) patients often develop nasal polyps. This case highlights functional endoscopic sinus surgery (FESS) providing symptom relief and improved facial appearance in a young CF patient with nasal polyposis.

Area of Science:

  • Otolaryngology
  • Pediatric Pulmonology
  • Medical Genetics

Background:

  • Cystic Fibrosis (CF) is a genetic disorder increasing the risk of sinonasal complications, including nasal polyposis.
  • Nasal polyps in CF patients can lead to significant upper airway obstruction and facial deformities.
  • The efficacy of early surgical intervention for CF-related nasal polyposis remains debated.

Observation:

  • A 17-month-old child with CF presented with hypertelorism, astigmatism, nasal discharge, and noisy breathing.
  • Imaging revealed bilateral ethmoid mucoceles.
  • Surgical findings included bilateral soft tissue masses obstructing the nasal cavity.

Findings:

  • Histological examination confirmed inflammatory nasal polyposis characteristic of CF.
  • The patient underwent polypectomy and bilateral mega-antrostomies.
  • Post-operative assessment showed significant relief of upper airway symptoms and normalization of facial appearance.

Implications:

  • This case suggests potential benefits of functional endoscopic sinus surgery (FESS) for symptom management in pediatric CF patients with nasal polyposis.
  • While recurrence rates are a concern, FESS may improve quality of life and cosmetic outcomes.
  • Further research is needed to define the optimal surgical timing and long-term impact of FESS in this population.

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