Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Photoreceptors and Visual Pathways

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...

Accessory Structures of the Eye

Accessory Structures of the Eye

Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Ophthalmic Drug Delivery Systems

Ophthalmic Drug Delivery Systems

Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Complications associated with subpalpebral lavage systems in upper and lower equine eyelids: A prospective, randomised study in 73 cases (2015-2024).

Equine veterinary journal·2025

Same author

Chemotherapeutics in Equine Practice.

The Veterinary clinics of North America. Equine practice·2024

Same author

Interspecies comparative morphological evaluation of the corneal epithelial stem cell niche: a pilot observational study.

Journal of veterinary science·2022

Same author

Risk factors for a first episode of primary uveitis in the UK and proportion of cases that experience recurrence following this first episode.

Equine veterinary journal·2022

Same author

An Analysis of Risk Factors for a Fracture or Luxation in Recovery From General Anesthesia in Horses: A Single Centre Study<sup>☆</sup>.

Journal of equine veterinary science·2022

Same author

Equine uveitis in the UK: a retrospective study (2008-2018).

The Veterinary record·2019

Search research articles

Related Experiment Video

Updated: Mar 19, 2026

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Ophthalmologic Disorders in Aged Horses.

Fernando Malalana¹

¹Philip Leverhulme Equine Hospital, University of Liverpool, Leahurst Campus, Chester High Road, Neston CH64 7TE, UK.

The Veterinary Clinics of North America. Equine Practice

|June 23, 2016

Summary

Ocular abnormalities are common in aged horses, potentially causing discomfort. Early detection and treatment are crucial for maintaining equine welfare and vision, even if not always obvious to owners.

Keywords:

Blind Eye Geriatric Horse Uveitis

More Related Videos

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Published on: February 19, 2014

Intravitreal Injections in the Ovine Eye

Intravitreal Injections in the Ovine Eye

Published on: July 5, 2022

Related Experiment Videos

Last Updated: Mar 19, 2026

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Published on: February 19, 2014

Intravitreal Injections in the Ovine Eye

Intravitreal Injections in the Ovine Eye

Published on: July 5, 2022

Area of Science:

Veterinary Ophthalmology
Equine Health

Background:

Ocular abnormalities are frequently observed in aging horses.
These conditions may not always cause apparent vision loss but can lead to discomfort.
Some abnormalities are age-specific, while others result from long-standing or advanced ocular disease.

Purpose of the Study:

To highlight the prevalence and significance of ocular abnormalities in aged horses.
To emphasize the importance of early detection and management of these conditions.
To underscore the implications for equine welfare and safety when vision is compromised.

Main Methods:

Review of common ocular conditions in geriatric equine populations.
Clinical observation and diagnostic approaches for equine eye diseases.
Assessment of the impact of ocular abnormalities on equine welfare.

Main Results:

A significant percentage of aged horses exhibit ocular abnormalities.
Chronic discomfort and potential vision impairment are key concerns.
The progression of underlying diseases exacerbates ocular damage in older horses.

Conclusions:

Routine ophthalmic examinations are vital for aged horses.
Prompt intervention can alleviate discomfort and preserve vision.
Addressing ocular issues is essential for ensuring the well-being and safety of aging horses.