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Updated: Mar 19, 2026

A Coupled Experiment-finite Element Modeling Methodology for Assessing High Strain Rate Mechanical Response of Soft Biomaterials
Published on: May 18, 2015
Finite element modeling of finite deformable, biphasic biological tissues with transversely isotropic statistically
John Z Wu1, Walter Herzog2, Salvatore Federico3
1National Institute for Occupational Safety and Health Morgantown, WV, USA jwu@cdc.gov.
Abstract:
The distribution of collagen fibers across articular cartilage layers is statistical in nature. Based on the concepts proposed in previous models, we developed a methodology to include the statistically distributed fibers across the cartilage thickness in the commercial FE software COMSOL which avoids extensive routine programming. The model includes many properties that are observed in real cartilage: finite hyperelastic deformation, depth-dependent collagen fiber concentration, depth- and deformation-dependent permeability, and statistically distributed collagen fiber orientation distribution across the cartilage thickness. Numerical tests were performed using confined and unconfined compressions. The model predictions on the depth-dependent strain distributions across the cartilage layer are consistent with the experimental data in the literature.
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