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Related Experiment Videos

Effect of intrathecal baclofen on bladder and sphincter function.

J B Nanninga1, F Frost, R Penn

  • 1Department of Urology, Northwestern University Medical School, Chicago, Illinois.

The Journal of Urology
|July 1, 1989
PubMed
Summary

A programmable baclofen pump improved severe spasticity and enhanced bladder and sphincter function in patients. This device offers value for managing lower urinary tract issues in spasticity-related conditions.

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Area of Science:

  • Neurology
  • Urology
  • Biomedical Engineering

Background:

  • Severe spasticity significantly impacts patient quality of life.
  • Spasticity often leads to complications in bladder and sphincter function.
  • Existing treatments for spasticity-related lower urinary tract dysfunction can be limited.

Purpose of the Study:

  • To evaluate the efficacy of a programmable baclofen pump in managing severe spasticity.
  • To assess the impact of baclofen pump therapy on lower urinary tract function, specifically bladder and sphincter control.
  • To determine the potential of this system in improving urological outcomes for patients with spasticity.

Main Methods:

  • Implantation of a programmable baclofen pump in seven patients with severe spasticity.

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  • Monitoring of patient symptoms and functional outcomes pre- and post-implantation.
  • Assessment of changes in bladder and sphincter function.

    • Main Results:

    • All seven patients reported relief from severe spasticity following pump implantation.
    • Significant improvements were observed in bladder function among the treated patients.
    • Enhanced sphincter control was noted, contributing to better urinary continence.

    Conclusions:

    • Programmable baclofen pump therapy is effective in alleviating severe spasticity.
    • The system demonstrates considerable value in improving lower urinary tract function, including bladder and sphincter control.
    • This therapeutic approach offers a promising solution for patients suffering from spasticity-induced urological dysfunction.