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Translocation t(9;11)(p23;q12): a primary chromosomal change in renal oncocytoma
T A Walter1, R D Pennington, H J Decker
1Cancer Center of Southwest Biomedical Research Institute, Scottsdale and Good Samaritan Medical Center, Phoenix, Arizona.
The Journal of Urology
|July 1, 1989
Abstract:
We report the cytogenetic, clinical, radiological and pathological features of a renal oncocytoma, diagnosed accidentally in a 50-year-old man who originally presented with symptoms related to prostatic hyperplasia. All metaphases examined showed a structural chromosomal rearrangement t(9;11)(p23;q12) as the only change. The constitutional karyotype was established as 46XY. We believe that this karyotypic anomaly may represent a primary and possibly specific change characterizing this uncommon and generally benign type of tumor.