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Updated: Mar 19, 2026

Microarray Analysis for Saccharomyces cerevisiae
Published on: April 7, 2011
Genome annotation of a Saccharomyces sp. lager brewer's yeast
Patricia Marcela De León-Medina1, Ramiro Elizondo-González1, Luis Cástulo Damas-Buenrostro2
1Instituto de Biotecnología, Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León. Pedro de Alba y Manuel L. Barragán S/N, Ciudad Universitaria, San Nicolás de los Garza, Nuevo León 66450, Mexico; Centro de Investigación y Desarrollo en Ciencias de la Salud, Universidad Autónoma de Nuevo León, Avenida Carlos Canseco s/n esquina con Av. Gonzalitos, Mutualismo, Mitras Centro, 64460 Monterrey, Nuevo León, Mexico; Laboratorio de Investigación y Desarrollo, Cervecería Cuauhtémoc Moctezuma S.A. de C.V., Alfonso Reyes Norte Col, Bella Vista, 2202 Monterrey, Nuevo León, Mexico.
Abstract:
The genome of lager brewer's yeast is a hybrid, with Saccharomyces eubayanus and Saccharomyces cerevisiae as sub-genomes. Due to their specific use in the beer industry, relatively little information is available. The genome of brewing yeast was sequenced and annotated in this study. We obtained a genome size of 22.7 Mbp that consisted of 133 scaffolds, with 65 scaffolds larger than 10 kbp. With respect to the annotation, 9939 genes were obtained, and when they were submitted to a local alignment, we found that 53.93% of these genes corresponded to S. cerevisiae, while another 42.86% originated from S. eubayanus. Our results confirm that our strain is a hybrid of at least two different genomes.
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