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Updated: Mar 19, 2026

A Complete Pipeline for Isolating and Sequencing MicroRNAs, and Analyzing Them Using Open Source Tools
Published on: August 21, 2019
Data on differentially expressed microRNAs in the liver between nonalcoholic fatty liver disease and normal Wistar
Deqing Zhang1, Yuqian Wang2, Zhibin Ji2
1Shandong Key Laboratory of Animal Biotechnology and Disease Control and Prevention, College of Animal Science and Technology, Shandong Agricultural University, Taian 271018, PR China; Laboratory Department, Taian Central Hospital, Taian 271000, PR China.
Abstract:
The dataset includes data from the Solexa sequencing reported in our paper: "Identification and differential expression of microRNAs associated with fat deposition in the liver of Wistar rats with nonalcoholic fatty liver disease" [1]. The data collected include small RNAs and microRNAs in liver tissue from high glucose-induced NAFLD Wistar rats, using normal Wistar rats as their negative controls. 6 small RNA libraries were constructed and the expression profiles were compared between the two groups. Here we describe in detail how the data, deposited in the Gene Expression Omnibus (GEO) with the accession number GEO: GSE68411, was generated including the basic analysis.

